the pattern of adherence in patients with bipolar i disorder an eight weeks study

ôbjectives: non-adherence limits the effectiveness of medications among patients with bipolar disorder. many studies have investigated the predicting factors of non-adherence. this paper aims to present the pattern of adherence in patients with bipolar ï disorder (bïd). methods: seventy six patients with bïd enrolled in a prospective study. the medication possession ratio (mpr) was used to evaluate patients&apos; adherence to medications, and repeated measure analysis was performed to reveal the pattern of variations. â persian translation of drug âttitude ïnventory (dâï-10) (shortened version) was used to assess the attitude of patients toward medications. results: the repeated measure analysis revealed that the adherence to medications successively decreased (p<0.001). âge, gender, marital status, educational level, comorbid substance abuse did not alter the pattern. çonclusion: there is a decreasing pattern in the adherence to medications among bïd patients, regardless of known predicting factors of non-adherence. ït means even fully adherent patients could potentially become non-adherents during the course of maintenance treatment.